Sven's Lab


Welcome to Sven's Lab


   We are a small group embedded within the Chemical Genomics Centre in Dortmund, Germany, working on Therapeutic Transcriptome Modifications.

So what does that mean?

   In general, our genome (DNA) is converted in a very tightly regulated processes ('Transcription') into RNA molecules. Afterwards protein synthesis takes place in a process called 'Translation'. Once certain key players of Transcription are mutated and cannot do their job as usual we exhibit diseases like various types of cancer, fibrosis or neuronal disorders. Our group tries to fix the defective Transcription of cells by modulating the activity of the molecules involved in this process.

   What we exactly do to achieve this and how we want to target such a goal, you will find in the Scientific Project Section.

 

The Central Dogma of Molecular Biology by Francis H. C. Crick, 'On Protein Synthesis', Manuscript 1956. Orange Box indicates where we want to adjust disease states within cells using different strategies (see Scientific Projects for details).
The Central Dogma of Molecular Biology by Francis H. C. Crick, 'On Protein Synthesis', Manuscript 1956. Orange Box indicates where we want to adjust disease states within cells using different strategies (see Scientific Projects for details).

 










  Hopefully, you find some sort of interesting information. If you liked it, leave a message in my guestbook. If you miss something, please get in touch!

Are you a colleague working in some sort of related field: Don't hesitate to contact me. As a student looking for some interesting lab experience - here you go!