Welcome to Sven's Lab
We are a small group embedded within the Chemical Genomics Centre in Dortmund, Germany, working on Therapeutic Transcriptome Modifications.
So what does that mean?
In general, our genome (DNA) is converted in a very tightly regulated processes ('Transcription') into RNA molecules. Afterwards protein synthesis takes place in a process called 'Translation'. Once certain key players of Transcription are mutated and cannot do their job as usual we exhibit diseases like various types of cancer, fibrosis or neuronal disorders. Our group tries to fix the defective Transcription of cells by modulating the activity of the molecules involved in this process.
What we exactly do to achieve this and how we want to target such a goal, you will find in the Scientific Project Section.